Nephrotic syndrome

nephrotic syndrome: A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 N04#
Hospital discharge: ICD-9 581
Hospital discharge: ICD-8 581
Cause of death: ICD-10 N04#
Cause of death: ICD-9 581
Cause of death: ICD-8 581

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector N14_NEPHROTICSYND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N00-N08
Name in latin Syndroma nephroticum

Summary Statistics

Key figures

All Female Male
Number of individuals 555 233 322
Unadjusted prevalence (%) 0.21 0.16 0.28
Mean age at first event (years) 42.99 39.51 45.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.64 [1.28, 5.46] 8.6e-3 83
15 years 0.03 3.88 [2.14, 7.02] 8.0e-6 76
5 years 0.01 7.70 [4.54, 13.06] 3.7e-14 44
1 year - - - -

Correlations

Index endpoint: N14_NEPHROTICSYND – Nephrotic syndrome
GWS hits: 1

Survival analyses between endpoints

Plot

before Nephrotic syndrome
after Nephrotic syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nephrotic syndrome