Urolithiasis

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 N20-N23
Cause of death: ICD-10 N20-N23

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6461 2141 4320
Unadjusted prevalence (%) 2.48 1.46 3.82
Mean age at first event (years) 50.61 46.16 52.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [0.93, 1.51] 1.6e-1 800
15 years 0.01 1.34 [1.10, 1.64] 4.2e-3 569
5 years 0.00 2.16 [1.75, 2.65] 2.7e-13 212
1 year 0.00 2.96 [2.15, 4.08] 2.9e-11 53

Correlations

Index endpoint: N14_UROLITHIASIS – Urolithiasis
GWS hits: 13

Survival analyses between endpoints

Plot

before Urolithiasis
after Urolithiasis

loading spinner Loading survival analyses plot