Nonalcoholic fatty liver disease

non-alcoholic fatty liver disease: A term referring to fatty replacement of the hepatic parenchyma which is not related to alcohol use.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K76.0
Cause of death: ICD-10 K76.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector NAFLD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K76
Name in latin Degeneratio adiposa hepatis non alibi classificata

Summary Statistics

Key figures

All Female Male
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Number of individuals
1135 625 510
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Unadjusted prevalence (%)
0.44 0.43 0.45
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Mean age at first event (years)
52.70 53.92 51.20

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Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.45 [1.37, 8.70] 8.5e-3 78
15 years 0.03 5.06 [2.50, 10.23] 6.5e-6 75
5 years 0.01 9.81 [5.68, 16.95] 2.7e-16 38
1 year 0.00 16.93 [8.50, 33.72] 8.3e-16 13

Correlations

Index endpoint: NAFLD – Nonalcoholic fatty liver disease
GWS hits: 2

Survival analyses between endpoints

Plot

before Nonalcoholic fatty liver disease
after Nonalcoholic fatty liver disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nonalcoholic fatty liver disease