Nonalcoholic fatty liver disease

non-alcoholic fatty liver disease: A term referring to fatty replacement of the hepatic parenchyma which is not related to alcohol use.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K76.0
Cause of death: ICD-10 K76.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector NAFLD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K76
Name in latin Degeneratio adiposa hepatis non alibi classificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 1135 625 510
Unadjusted prevalence (%) 0.44 0.43 0.45
Mean age at first event (years) 52.70 53.92 51.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.45 [1.37, 8.70] 8.5e-3 78
15 years 0.03 5.06 [2.50, 10.23] 6.5e-6 75
5 years 0.01 9.81 [5.68, 16.95] 2.7e-16 38
1 year 0.00 16.93 [8.50, 33.72] 8.3e-16 13

Correlations

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Index endpoint: NAFLD – Nonalcoholic fatty liver disease
GWS hits: 2

Survival analyses between endpoints

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Plot

before Nonalcoholic fatty liver disease
after Nonalcoholic fatty liver disease

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Drugs most likely to be purchased after Nonalcoholic fatty liver disease

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