COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia

DOID EFO MESH SNOMED PheWeb

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

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FinnGen phenotype data

Filter registries None

Check pre-conditions None

Include endpoints

PNEUMONIA

SEPTICHE_PNEUMONIA

Check conditions None

Apply sex-specific rule None

PULM_PNEUMONIA_SEPSIS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	34103	15092	19011
Unadjusted prevalence (%)	13.11	10.27	16.81
Mean age at first event (years)	54.33	51.52	56.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.11	7.88 [7.13, 8.71]	<1e-100	9169
15 years	0.07	9.63 [8.83, 10.51]	<1e-100	8749
5 years	0.03	19.83 [18.29, 21.51]	<1e-100	6752
1 year	0.01	52.30 [46.06, 59.38]	<1e-100	4234

Correlations

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Index endpoint: PULM_PNEUMONIA_SEPSIS – COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia
GWS hits: 2

Survival analyses between endpoints

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Plot

before COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia
after COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia

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Table

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Drugs most likely to be purchased after COPD/asthma/ILD related pneumonia or pneumonia derived septichaemia

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