Congenital malformations, deformations and chromosomal abnormalities

PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 Q00-Q99

Hospital discharge: ICD-9 7[4-5]

Hospital discharge: ICD-8 7[4-5]

Cause of death: ICD-10 Q00-Q99

Cause of death: ICD-9 7[4-5]

Cause of death: ICD-8 7[4-5]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI

Extra metadata

Level in the ICD hierarchy 1

Special XVII_MALFORMAT_ABNORMAL

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Congenital malformations, deformations and chromosomal abnormalities based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	15201	9192	6009
Unadjusted prevalence (%)	5.85	6.26	5.31
Mean age at first event (years)	29.59	30.32	28.46

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.82 [1.46, 2.28]	1.5e-7	744
15 years	0.01	2.21 [1.82, 2.69]	8.5e-16	526
5 years	0.00	3.44 [2.81, 4.21]	5.3e-33	185
1 year	0.00	5.44 [3.97, 7.45]	4.0e-26	53

Correlations

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Index endpoint: Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI – Congenital malformations, deformations and chromosomal abnormalities
GWS hits:

Survival analyses between endpoints

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Plot

before Congenital malformations, deformations and chromosomal abnormalities
after Congenital malformations, deformations and chromosomal abnormalities

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Table

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Drugs most likely to be purchased after Congenital malformations, deformations and chromosomal abnormalities

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