Codeine or tramadol medication

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RX_CODEINE_TRAMADOL

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 37706 21956 15750
Unadjusted prevalence (%) 14.50 14.94 13.93
Mean age at first event (years) 54.98 53.46 57.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.47 [3.04, 3.96] 4.7e-77 2093
15 years 0.02 3.54 [3.12, 4.01] 1.4e-86 2091
5 years 0.00 4.27 [3.77, 4.83] <1e-100 1061
1 year 0.00 3.76 [3.08, 4.60] 3.1e-38 171

Correlations

Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 2

Survival analyses between endpoints

Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication