First line medication for Crohns disease

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC A07EC|H02AB
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RX_CROHN_1STLINE

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 50234 30127 20107
Unadjusted prevalence (%) 19.32 20.50 17.78
Mean age at first event (years) 51.18 48.85 54.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.52 [2.28, 2.79] 7.2e-72 5622
15 years 0.02 2.92 [2.69, 3.18] <1e-100 4601
5 years 0.01 5.21 [4.79, 5.68] <1e-100 2188
1 year 0.00 7.15 [6.20, 8.25] <1e-100 570

Correlations

Index endpoint: RX_CROHN_1STLINE – First line medication for Crohns disease
GWS hits: 12

Survival analyses between endpoints

Plot

before First line medication for Crohns disease
after First line medication for Crohns disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after First line medication for Crohns disease