Second line medication for Crohns disease

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC L04AX|L01BB02
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RX_CROHN_2NDLINE

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 13437 8356 5081
Unadjusted prevalence (%) 5.17 5.69 4.49
Mean age at first event (years) 50.99 50.25 52.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.60 [2.03, 3.33] 3.0e-14 662
15 years 0.02 2.96 [2.38, 3.68] 1.3e-22 620
5 years 0.00 4.21 [3.43, 5.17] 9.7e-43 253
1 year 0.00 3.31 [2.31, 4.75] 7.5e-11 39

Correlations

Index endpoint: RX_CROHN_2NDLINE – Second line medication for Crohns disease
GWS hits: 13

Survival analyses between endpoints

Plot

before Second line medication for Crohns disease
after Second line medication for Crohns disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Second line medication for Crohns disease