Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
TBC_RESP
Extra metadata
First used in FinnGen datafreeze
DF2
Respiratory tuberculosis
pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.
TBC_RESP
Similar endpoints
↥List of similar endpoints to
Respiratory tuberculosis
based on the number of shared cases.
Broader endpoints:
- Respiratry tuberculosis
- Tuberculosis
- Tuberculosis, IBD comorbidity
- Tuberculosis
- Infections, IBD-co-morbidities
Narrower endpoints:
- Respiratry tuberculosis
- Respiratory tuberculosis, not confirmed bacteriologically or histologically
- Respiratory TBC, ICD-8 codes not specifying whether confirmed bacteriologically or histologically
- Respiratory tuberculosis, bacteriologically and histologically confirmed
- Respiratory tuberculosis, bacteriologically and histologically confirmed
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1087 | 432 | 655 |
| Unadjusted prevalence (%) | 0.42 | 0.29 | 0.58 |
| Mean age at first event (years) | 44.78 | 40.25 | 47.78 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.04 | 2.74 [1.74, 4.30] | 1.2e-5 | 315 |
| 15 years | 0.02 | 3.07 [2.20, 4.28] | 3.4e-11 | 239 |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: TBC_RESP – Respiratory tuberculosis
GWS hits: 0
Survival analyses between endpoints
↥Plot
before Respiratory tuberculosis
after Respiratory tuberculosis
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Table
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