primary myelofibrosis: Myelofibrosis with myeloid metaplasia is a myeloproliferative disease with annual incidence of approximately 1 case per 100,000 individuals and age at diagnosis around 60 (an increased prevalence is noted in Ashkenazi Jews). Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly, portal hypertension.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
THROMBOCYTAEMIA
Extra metadata
List of similar endpoints to
Essential (haemorrhagic) thrombocythaemia
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 479 | 293 | 186 |
| Unadjusted prevalence (%) | 0.18 | 0.20 | 0.16 |
| Mean age at first event (years) | 59.55 | 58.33 | 61.45 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.43 [0.68, 3.02] | 3.5e-1 | 53 |
| 15 years | 0.01 | 1.97 [0.98, 3.95] | 5.8e-2 | 49 |
| 5 years | 0.00 | 3.77 [2.02, 7.02] | 3.0e-5 | 23 |
| 1 year | - | - | - | - |
Index endpoint: THROMBOCYTAEMIA – Essential (haemorrhagic) thrombocythaemia
GWS hits: 5
before Essential (haemorrhagic) thrombocythaemia
after Essential (haemorrhagic) thrombocythaemia
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