Diseases of the musculoskeletal system and connective tissue

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99
Hospital discharge: ICD-9 7[1-3]
Hospital discharge: ICD-8 7[1-3]
Cause of death: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-9 7[1-3]
Cause of death: ICD-8 7[1-3]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector XIII_MUSCULOSKELET

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 140327 81172 59155
Unadjusted prevalence (%) 53.97 55.24 52.31
Mean age at first event (years) 46.39 45.35 47.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.35 [1.26, 1.46] 1.1e-15 12013
15 years 0.01 1.56 [1.46, 1.67] 1.7e-39 8713
5 years 0.00 2.30 [2.13, 2.48] 3.1e-100 2982
1 year 0.00 3.25 [2.82, 3.75] 9.0e-60 787

Correlations

Index endpoint: XIII_MUSCULOSKELET – Diseases of the musculoskeletal system and connective tissue
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the musculoskeletal system and connective tissue
after Diseases of the musculoskeletal system and connective tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of the musculoskeletal system and connective tissue