Malignant neoplasm of anus and anal canal

DOID EFO MESH SNOMED PheWeb

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

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FinnGen phenotype data

Filter registries Death, Cancer

Cause of death: ICD-10 C21

Cause of death: ICD-9 154[2-3]

Cause of death: ICD-8 1542

Cancer registry: Topography ICD-O-3 C21

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

C3_ANUS_ANALCANAL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of anus and anal canal based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	161	95	66
Unadjusted prevalence (%)	0.06	0.06	0.06
Mean age at first event (years)	62.92	60.83	65.92

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.11	8.13 [3.11, 21.25]	1.9e-5	26
15 years	0.05	8.13 [3.11, 21.25]	1.9e-5	26
5 years	0.02	17.04 [7.91, 36.73]	4.6e-13	21
1 year	-	-	-	-

Correlations

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Index endpoint: C3_ANUS_ANALCANAL – Malignant neoplasm of anus and anal canal
GWS hits: 0

Survival analyses between endpoints

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Plot

before Malignant neoplasm of anus and anal canal
after Malignant neoplasm of anus and anal canal

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Table

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Drugs most likely to be purchased after Malignant neoplasm of anus and anal canal

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