Malignant neoplasm of anus and anal canal

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Death, Cancer

Cause of death: ICD-10 C21
Cause of death: ICD-9 154[2-3]
Cause of death: ICD-8 1542
Cancer registry: Topography ICD-O-3 C21

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector C3_ANUS_ANALCANAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 161 95 66
Unadjusted prevalence (%) 0.06 0.06 0.06
Mean age at first event (years) 62.92 60.83 65.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 8.13 [3.11, 21.25] 1.9e-5 26
15 years 0.05 8.13 [3.11, 21.25] 1.9e-5 26
5 years 0.02 17.04 [7.91, 36.73] 4.6e-13 21
1 year - - - -

Correlations

Index endpoint: C3_ANUS_ANALCANAL – Malignant neoplasm of anus and anal canal
GWS hits: 0

Survival analyses between endpoints

Plot

before Malignant neoplasm of anus and anal canal
after Malignant neoplasm of anus and anal canal

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Drugs most likely to be purchased after Malignant neoplasm of anus and anal canal