Malignant neoplasm, wide definition for exclusion

PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 C

Hospital discharge: ICD-9 1[4-9]|20

Hospital discharge: ICD-8 1[4-9]|20

Cause of death: ICD-10 C

Cause of death: ICD-9 1[4-9]|20

Cause of death: ICD-8 1[4-9]|20

KELA reimbursements: KELA codes 115|116

Check pre-conditions None

Include endpoints

C3_LIP_ORAL_PHARYNX

C3_DIGESTIVE_ORGANS

C3_BONE_CARTILAGE

C3_SKIN

C3_MESTOTHEL_SOFTTISSUE

C3_BREAST

C3_FEMALE_GENITAL

C3_MALE_GENITAL

C3_URINARY_TRACT

C3_EYE_BRAIN_NEURO

C3_ENDOCRINE

C3_UNCERTAIN_SECONDARY

CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC

CD2_INDEPENDENT_MULTIPLE_SITES

Check conditions None

Apply sex-specific rule None

C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Malignant neoplasm, wide definition for exclusion based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	56318	30078	26240
Unadjusted prevalence (%)	21.66	20.47	23.20
Mean age at first event (years)	60.81	57.50	64.61

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.52 [4.16, 4.91]	<1e-100	10865
15 years	0.04	5.53 [5.13, 5.95]	<1e-100	9898
5 years	0.01	13.08 [12.09, 14.16]	<1e-100	6593
1 year	0.00	35.12 [30.42, 40.56]	<1e-100	3404

Correlations

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Index endpoint: C3_CANCER_WIDE – Malignant neoplasm, wide definition for exclusion
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm, wide definition for exclusion
after Malignant neoplasm, wide definition for exclusion

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Table

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Drugs most likely to be purchased after Malignant neoplasm, wide definition for exclusion

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