Malignant neoplasm of breast, HER2-negative

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Death, Cancer

Cause of death: ICD-10 C50

Cause of death: ICD-9 174

Cause of death: ICD-8 174

Cancer registry: Topography ICD-O-3 C50

Check pre-conditions None

Include endpoints None

Check conditions

not RX_HER2PLUS

Apply sex-specific rule

Sex only females

C3_BREAST_HER2NEG

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF5

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List of similar endpoints to Malignant neoplasm of breast, HER2-negative based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.56 [1.09, 2.25]	1.6e-2	912
15 years	0.02	1.90 [1.42, 2.55]	1.5e-5	756
5 years	0.00	3.14 [2.49, 3.96]	6.5e-22	348
1 year	0.00	3.19 [2.34, 4.36]	2.9e-13	70

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Index endpoint: C3_BREAST_HER2NEG – Malignant neoplasm of breast, HER2-negative
GWS hits: 32

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before Malignant neoplasm of breast, HER2-negative
after Malignant neoplasm of breast, HER2-negative

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