Malignant neoplasm of skin

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector C3_SKIN

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 13706 6653 7053
Unadjusted prevalence (%) 5.27 4.53 6.24
Mean age at first event (years) 64.55 62.92 66.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.55 [1.32, 1.81] 8.6e-8 2031
15 years 0.01 1.87 [1.64, 2.13] 1.0e-20 1748
5 years 0.00 2.84 [2.51, 3.21] 5.7e-62 837
1 year - - - -

Correlations

Index endpoint: C3_SKIN – Malignant neoplasm of skin
GWS hits: 53

Survival analyses between endpoints

Plot

before Malignant neoplasm of skin
after Malignant neoplasm of skin

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Drugs most likely to be purchased after Malignant neoplasm of skin