Malignant neoplasm of breast, HER-positive

No definition available.

Endpoint definition

FinnGen phenotype data
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Filter registries Death, Cancer

Cause of death: ICD-10 C50
Cause of death: ICD-9 174
Cause of death: ICD-8 174
Cancer registry: Topography ICD-O-3 C50

Check pre-conditions None

Include endpoints None

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Check conditions

RX_HERPLUS
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Apply sex-specific rule

Sex only females
diagram downward connector C3_BREAST_HERPLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 6363 6363 -
Unadjusted prevalence (%) 2.45 4.33 -
Mean age at first event (years) 59.48 59.48 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.44 [1.84, 3.24] 6.5e-10 448
15 years 0.02 2.71 [2.10, 3.50] 1.4e-14 384
5 years 0.00 3.34 [2.59, 4.31] 1.5e-20 149
1 year - - - -

Correlations

Index endpoint: C3_BREAST_HERPLUS – Malignant neoplasm of breast, HER-positive
GWS hits: 20

Survival analyses between endpoints

Plot

before Malignant neoplasm of breast, HER-positive
after Malignant neoplasm of breast, HER-positive

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Drugs most likely to be purchased after Malignant neoplasm of breast, HER-positive