Malignant neoplasm of endocrine gland

endocrine neoplasm: A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector C3_ENDOCRINE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4

Similar endpoints

List of similar endpoints to Malignant neoplasm of endocrine gland based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 1369 1001 368
Unadjusted prevalence (%) 0.53 0.68 0.33
Mean age at first event (years) 49.38 48.22 52.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.93 [1.64, 5.23] 2.8e-4 104
15 years 0.02 3.60 [2.07, 6.25] 5.6e-6 90
5 years 0.01 7.27 [4.41, 11.99] 7.6e-15 54
1 year - - - -

Correlations

Index endpoint: C3_ENDOCRINE – Malignant neoplasm of endocrine gland
GWS hits: 5

Survival analyses between endpoints

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before Malignant neoplasm of endocrine gland
after Malignant neoplasm of endocrine gland

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Drugs most likely to be purchased after Malignant neoplasm of endocrine gland