Malignant neoplasm of meninges

DOID EFO MESH PheWeb

obsolete_meningioma: ['A tumor of meningothelial cells that are manifested in the central nervous system and arise from the arachnoid "cap" cells of the arachnoid villi in the meninges.']

Endpoint definition

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FinnGen phenotype data

Filter registries Death, Cancer

Cause of death: ICD-10 C70

Cause of death: ICD-9 1921|1923

Cause of death: ICD-8 192[1-2]

Cancer registry: Topography ICD-O-3 C70

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

C3_MENINGES

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of meninges based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	848	621	227
Unadjusted prevalence (%)	0.33	0.42	0.20
Mean age at first event (years)	58.18	57.46	60.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.38 [2.69, 7.13]	2.7e-9	120
15 years	0.03	5.22 [3.32, 8.23]	1.0e-12	108
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: C3_MENINGES – Malignant neoplasm of meninges
GWS hits: 1

Survival analyses between endpoints

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Plot

before Malignant neoplasm of meninges
after Malignant neoplasm of meninges

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Table

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Drugs most likely to be purchased after Malignant neoplasm of meninges

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