neoplasm of mature B-cells: A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
CD2_FOLLICULAR_LYMPHOMA
Extra metadata
List of similar endpoints to
Follicular lymphoma
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 614 | 310 | 304 |
| Unadjusted prevalence (%) | 0.24 | 0.21 | 0.27 |
| Mean age at first event (years) | 61.79 | 61.35 | 62.24 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.31 [1.63, 6.70] | 9.0e-4 | 91 |
| 15 years | 0.03 | 4.02 [2.18, 7.43] | 9.1e-6 | 85 |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Index endpoint: CD2_FOLLICULAR_LYMPHOMA – Follicular lymphoma
GWS hits: 1
before Follicular lymphoma
after Follicular lymphoma
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