Organ-limited amyloidosis

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E85.4
Cause of death: ICD-10 E85.4

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_AMYL_ORGAN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E85
Name in latin Amyloidosis in uno organo

Summary Statistics

Key figures

All Female Male
Number of individuals 49 20 29
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 69.70 65.35 72.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: E4_AMYL_ORGAN – Organ-limited amyloidosis
GWS hits:

Survival analyses between endpoints

Plot

before Organ-limited amyloidosis
after Organ-limited amyloidosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Organ-limited amyloidosis