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Congenital iodine-deficiency syndrome/hypothyroidism

DOIDEFOMESHSNOMED PheWeb

thyroid disease: A disease involving the thyroid gland.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E00, E03.0, E03.1
Hospital discharge: ICD-9 243
Hospital discharge: ICD-8 243
Cause of death: ICD-10 E00, E03.0, E03.1
Cause of death: ICD-9 243
Cause of death: ICD-8 243

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_CONGEIOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 518 423 95
Unadjusted prevalence (%) 0.20 0.29 0.08
Mean age at first event (years) 54.23 53.15 59.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.92 [2.99, 11.73] 3.5e-7 64
15 years 0.04 5.61 [2.77, 11.34] 1.6e-6 59
5 years 0.01 6.27 [3.08, 12.76] 4.1e-7 38
1 year - - - -

Correlations

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Index endpoint: E4_CONGEIOD – Congenital iodine-deficiency syndrome/hypothyroidism
GWS hits: 3

Survival analyses between endpoints

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Plot

before Congenital iodine-deficiency syndrome/hypothyroidism
after Congenital iodine-deficiency syndrome/hypothyroidism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Congenital iodine-deficiency syndrome/hypothyroidism

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