Other and/or unspecified nontoxic goitre

goiter: Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.8, E04.9
Hospital discharge: ICD-9 2419
Cause of death: ICD-10 E04.8, E04.9
Cause of death: ICD-9 2419

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITRENAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1519 1286 233
Unadjusted prevalence (%) 0.58 0.88 0.21
Mean age at first event (years) 54.25 53.40 58.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [0.79, 1.74] 4.3e-1 101
15 years 0.01 1.53 [1.05, 2.22] 2.6e-2 77
5 years 0.00 2.82 [1.88, 4.24] 6.1e-7 36
1 year 0.00 5.16 [2.78, 9.58] 2.0e-7 12

Correlations

Index endpoint: E4_GOITRENAS – Other and/or unspecified nontoxic goitre
GWS hits: 5

Survival analyses between endpoints

Plot

before Other and/or unspecified nontoxic goitre
after Other and/or unspecified nontoxic goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and/or unspecified nontoxic goitre