Acute appendicitis, with complications

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector APPENDACUT_COMPLIC

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 4495 2148 2347
Unadjusted prevalence (%) 1.73 1.46 2.08
Mean age at first event (years) 35.61 33.98 37.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.12 [0.80, 1.57] 5.3e-1 397
15 years 0.01 1.26 [0.94, 1.68] 1.3e-1 261
5 years 0.00 1.94 [1.44, 2.62] 1.6e-5 84
1 year 0.00 3.11 [1.97, 4.91] 1.1e-6 24

Correlations

Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 1

Survival analyses between endpoints

Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications