Acute appendicitis, with complications

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector APPENDACUT_COMPLIC

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 4495 2148 2347
Unadjusted prevalence (%) 1.73 1.46 2.08
Mean age at first event (years) 35.61 33.98 37.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.12 [0.80, 1.57] 5.3e-1 397
15 years 0.01 1.26 [0.94, 1.68] 1.3e-1 261
5 years 0.00 1.94 [1.44, 2.62] 1.6e-5 84
1 year 0.00 3.11 [1.97, 4.91] 1.1e-6 24

Correlations

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Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 1

Survival analyses between endpoints

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Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications

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