Diseases of appendix

DOID EFO MESH SNOMED PheWeb

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K35-K38

Cause of death: ICD-10 K35-K38

Check pre-conditions None

Include endpoints

K11_APPENDACUT

K11_APPENDOTH

K11_OTHAPPEND

Check conditions None

Apply sex-specific rule None

K11_APPENDIX

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of appendix based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

20326

11063

9263

Unadjusted prevalence (%)

7.82

7.53

8.19

Mean age at first event (years)

33.77

32.32

35.49

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Methods page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.16 [0.99, 1.36]	6.9e-2	1119
15 years	0.01	1.28 [1.10, 1.48]	9.5e-4	704
5 years	0.00	1.71 [1.43, 2.03]	2.4e-9	201
1 year	0.00	2.58 [1.91, 3.48]	6.8e-10	54

Correlations

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Index endpoint: K11_APPENDIX – Diseases of appendix
GWS hits: 7

Survival analyses between endpoints

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Plot

before Diseases of appendix
after Diseases of appendix

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Table

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Drugs most likely to be purchased after Diseases of appendix

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