Malignant neoplasm of breast, HER-negative

No definition available.

Endpoint definition

FinnGen phenotype data
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Filter registries Death, Cancer

Cause of death: ICD-10 C50
Cause of death: ICD-9 174
Cause of death: ICD-8 174
Cancer registry: Topography ICD-O-3 C50

Check pre-conditions None

Include endpoints None

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Check conditions

not RX_HERPLUS
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Apply sex-specific rule

Sex only females
diagram downward connector C3_BREAST_HERNEG

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 4177 4177 -
Unadjusted prevalence (%) 1.61 2.84 -
Mean age at first event (years) 57.64 57.64 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.16 [0.86, 1.57] 3.4e-1 464
15 years 0.01 1.47 [1.12, 1.92] 4.8e-3 372
5 years 0.00 3.20 [2.53, 4.05] 2.2e-22 199
1 year 0.00 5.12 [3.74, 7.01] 1.9e-24 64

Correlations

Index endpoint: C3_BREAST_HERNEG – Malignant neoplasm of breast, HER-negative
GWS hits: 7

Survival analyses between endpoints

Plot

before Malignant neoplasm of breast, HER-negative
after Malignant neoplasm of breast, HER-negative

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Drugs most likely to be purchased after Malignant neoplasm of breast, HER-negative