Malignant neoplasm of cervix uteri

cervical carcinoma: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma.

Endpoint definition

FinnGen phenotype data
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Filter registries Death, Cancer

Cause of death: ICD-10 C53
Cause of death: ICD-9 180
Cause of death: ICD-8 180
Cancer registry: Topography ICD-O-3 C53

Check pre-conditions None

Include endpoints None

Check conditions None

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Apply sex-specific rule

Sex only females
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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 2229 2229 -
Unadjusted prevalence (%) 0.86 1.52 -
Mean age at first event (years) 38.15 38.15 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.21 [0.72, 2.03] 4.7e-1 103
15 years 0.01 1.46 [0.91, 2.33] 1.1e-1 70
5 years 0.00 3.74 [2.41, 5.79] 3.6e-9 39
1 year 0.00 4.87 [2.42, 9.79] 9.1e-6 10

Correlations

Index endpoint: C3_CERVIX_UTERI – Malignant neoplasm of cervix uteri
GWS hits: 1

Survival analyses between endpoints

Plot

before Malignant neoplasm of cervix uteri
after Malignant neoplasm of cervix uteri

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Drugs most likely to be purchased after Malignant neoplasm of cervix uteri