Follicular lymphoma

neoplasm of mature B-cells: A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 C82
Hospital discharge: ICD-9 2000A
Cause of death: ICD-10 C82
Cause of death: ICD-9 2000A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector CD2_FOLLICULAR_LYMPHOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Lymphoma non-Hodgkin nodulare (folliculare)

Summary Statistics

Key figures

All Female Male
Number of individuals 614 310 304
Unadjusted prevalence (%) 0.24 0.21 0.27
Mean age at first event (years) 61.79 61.35 62.24


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.31 [1.63, 6.70] 9.0e-4 91
15 years 0.03 4.02 [2.18, 7.43] 9.1e-6 85
5 years - - - -
1 year - - - -


Index endpoint: CD2_FOLLICULAR_LYMPHOMA – Follicular lymphoma
GWS hits: 1

Survival analyses between endpoints


before Follicular lymphoma
after Follicular lymphoma

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Drugs most likely to be purchased after Follicular lymphoma