breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.
Check pre-conditions None
Check conditions None
Apply sex-specific rule
CD2_INSITU_BREAST
Extra metadata
List of similar endpoints to
Carcinoma in situ of breast
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1373 | 1373 | - |
| Unadjusted prevalence (%) | 0.53 | 0.93 | - |
| Mean age at first event (years) | 59.15 | 59.15 | - |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.61 [0.93, 2.80] | 8.7e-2 | 57 |
| 15 years | 0.01 | 1.91 [1.15, 3.15] | 1.2e-2 | 52 |
| 5 years | 0.00 | 2.50 [1.40, 4.46] | 2.0e-3 | 23 |
| 1 year | - | - | - | - |
Index endpoint: CD2_INSITU_BREAST – Carcinoma in situ of breast
GWS hits: 1
before Carcinoma in situ of breast
after Carcinoma in situ of breast
Loading survival analyses plot
Loading survival analyses table