Multiple myeloma and malignant plasma cell neoplasms

multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 C90
Hospital discharge: ICD-9 203
Hospital discharge: ICD-8 203
Cause of death: ICD-10 C90
Cause of death: ICD-9 203
Cause of death: ICD-8 203

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector CD2_MULTIPLE_MYELOMA_PLASMA_CELL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Myeloma multiplex et neoplasmata maligna plasmacytorum

Summary Statistics

Key figures

All Female Male
Number of individuals 693 321 372
Unadjusted prevalence (%) 0.27 0.22 0.33
Mean age at first event (years) 65.19 64.70 65.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL – Multiple myeloma and malignant plasma cell neoplasms
GWS hits: 0

Survival analyses between endpoints

Plot

before Multiple myeloma and malignant plasma cell neoplasms
after Multiple myeloma and malignant plasma cell neoplasms

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Drugs most likely to be purchased after Multiple myeloma and malignant plasma cell neoplasms