Allergic purpura

Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D69.0
Hospital discharge: ICD-9 2870
Hospital discharge: ICD-8 2870
Cause of death: ICD-10 D69.0
Cause of death: ICD-9 2870
Cause of death: ICD-8 2870

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector D3_ALLERGPURPURA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D69
Name in latin Purpura allergica

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 555 328 227
Unadjusted prevalence (%) 0.21 0.22 0.20
Mean age at first event (years) 39.37 37.35 42.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.20 [2.58, 10.47] 3.9e-6 68
15 years 0.03 5.35 [2.87, 9.99] 1.4e-7 56
5 years 0.01 9.62 [5.23, 17.69] 3.1e-13 35
1 year - - - -

Correlations

Index endpoint: D3_ALLERGPURPURA – Allergic purpura
GWS hits: 0

Survival analyses between endpoints

Plot

before Allergic purpura
after Allergic purpura

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Allergic purpura