Allergic purpura

Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D69.0
Hospital discharge: ICD-9 2870
Hospital discharge: ICD-8 2870
Cause of death: ICD-10 D69.0
Cause of death: ICD-9 2870
Cause of death: ICD-8 2870

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector D3_ALLERGPURPURA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D69
Name in latin Purpura allergica

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 555 328 227
Unadjusted prevalence (%) 0.21 0.22 0.20
Mean age at first event (years) 39.37 37.35 42.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.20 [2.58, 10.47] 3.9e-6 68
15 years 0.03 5.35 [2.87, 9.99] 1.4e-7 56
5 years 0.01 9.62 [5.23, 17.69] 3.1e-13 35
1 year - - - -

Correlations

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Index endpoint: D3_ALLERGPURPURA – Allergic purpura
GWS hits: 0

Survival analyses between endpoints

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Plot

before Allergic purpura
after Allergic purpura

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Allergic purpura

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