Other coagulation defects

thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D68
Cause of death: ICD-10 D68

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector D3_COAGOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D65-D69
Name in latin Aliae defectus coagulationis

Similar endpoints

List of similar endpoints to Other coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 1097 731 366
Unadjusted prevalence (%) 0.42 0.50 0.32
Mean age at first event (years) 48.50 44.44 56.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 15.16 [8.56, 26.87] 1.2e-20 156
15 years 0.10 16.84 [9.72, 29.17] 7.0e-24 152
5 years - - - -
1 year - - - -

Correlations

Index endpoint: D3_COAGOTHER – Other coagulation defects
GWS hits: 10

Survival analyses between endpoints

Plot

before Other coagulation defects
after Other coagulation defects

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Drugs most likely to be purchased after Other coagulation defects