Endpoint definition
↥Check pre-conditions None
Include endpoints
Check conditions None
Apply sex-specific rule None
Extra metadata
obsolete_common variable immunodeficiency: ['A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM).', 'A primary immunodeficiency characterized by low levels or absence of all the immunoglobulin classes and lack of B-lymphocytes or plasma cells. It results in recurrent bacterial infections. Complications include autoimmune phenomena and cancer development.', 'Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.']
Check pre-conditions None
Include endpoints
Check conditions None
Apply sex-specific rule None
Extra metadata
List of similar endpoints to Common variable immunodeficiency based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
All | Female | Male | |
---|---|---|---|
Number of individuals | 111 | 72 | 39 |
Unadjusted prevalence (%) | 0.04 | 0.05 | 0.03 |
Mean age at first event (years) | 49.18 | 49.43 | 48.71 |
Follow-up | Absolute risk | HR [95% CI] | p | N |
---|---|---|---|---|
1998–2019 | - | - | - | - |
15 years | - | - | - | - |
5 years | - | - | - | - |
1 year | - | - | - | - |
Index endpoint: D3_CVID – Common variable immunodeficiency
GWS hits:
before Common variable immunodeficiency
after Common variable immunodeficiency
Loading survival analyses plot
Loading survival analyses table