Hereditary factor VIII deficiency

DOID EFO MESH PheWeb

obsolete_factor VIII deficiency: An X-linked disease that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D66

Hospital discharge: ICD-9 2860

Hospital discharge: ICD-8 2860

Cause of death: ICD-10 D66

Cause of death: ICD-9 2860

Cause of death: ICD-8 2860

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

D3_HEREDFVIIIDEF

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D65-D69

Name in latin Deficientia hereditaria factoris VIII

Similar endpoints

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List of similar endpoints to Hereditary factor VIII deficiency based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	44	16	28
Unadjusted prevalence (%)	0.02	0.01	0.02
Mean age at first event (years)	33.02	36.53	31.02

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: D3_HEREDFVIIIDEF – Hereditary factor VIII deficiency
GWS hits:

Survival analyses between endpoints

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Plot

before Hereditary factor VIII deficiency
after Hereditary factor VIII deficiency

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Table

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Drugs most likely to be purchased after Hereditary factor VIII deficiency

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