Idiopathic thrombocytopenic purpura

autoimmune thrombocytopenic purpura: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.

Endpoint definition

↥
FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D69.3
Hospital discharge: ICD-9 2873A
Hospital discharge: ICD-8 28710
Cause of death: ICD-10 D69.3
Cause of death: ICD-9 2873A
Cause of death: ICD-8 28710

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector D3_ITP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D69
Name in latin Purpura idiopathica thrombocytopenica

Similar endpoints

↥

List of similar endpoints to Idiopathic thrombocytopenic purpura based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 494 263 231
Unadjusted prevalence (%) 0.19 0.18 0.20
Mean age at first event (years) 48.32 42.99 54.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.04 [1.43, 6.47] 3.8e-3 68
15 years 0.02 3.65 [1.85, 7.19] 1.9e-4 58
5 years 0.01 7.69 [4.36, 13.56] 1.8e-12 33
1 year - - - -

Correlations

↥

Index endpoint: D3_ITP – Idiopathic thrombocytopenic purpura
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Idiopathic thrombocytopenic purpura
after Idiopathic thrombocytopenic purpura

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Idiopathic thrombocytopenic purpura

↥