Severe non-proliferative background diabetic retinopathy

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H36.02*
Cause of death: ICD-10 H36.02*

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_BCKGRND_RETINA_NONPROLIF

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 568 241 327
Unadjusted prevalence (%) 0.22 0.16 0.29
Mean age at first event (years) 45.80 44.15 47.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 10.05 [6.00, 16.85] 2.1e-18 65
15 years 0.07 10.47 [6.16, 17.79] 3.7e-18 63
5 years 0.01 12.59 [7.12, 22.27] 3.0e-18 35
1 year - - - -

Correlations

Index endpoint: DM_BCKGRND_RETINA_NONPROLIF – Severe non-proliferative background diabetic retinopathy
GWS hits: 2

Survival analyses between endpoints

Plot

before Severe non-proliferative background diabetic retinopathy
after Severe non-proliferative background diabetic retinopathy

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Drugs most likely to be purchased after Severe non-proliferative background diabetic retinopathy