Diabetes-related co-morbidities/complications

PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries None

Check pre-conditions None

Include endpoints

I9_ISCHHEART

C_STROKE

DM_PERIPHATHERO

DM_NEPHROPATHY

DM_NEPHORAPATHY_OPER

DM_RETINOPATHY

CHARCOT

DM_NEUROPATHY

DM_PERIPH_ANGIOPATHY

DM_SEVERAL_COMPLICATIONS

DM_KETOACIDOSIS

DM_HYPOGLYC

Check conditions None

Apply sex-specific rule None

DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diabetes-related co-morbidities/complications based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	69524	29500	40024
Unadjusted prevalence (%)	26.74	20.07	35.39
Mean age at first event (years)	58.91	58.86	58.95

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.82 [5.42, 6.26]	<1e-100	15225
15 years	0.04	7.27 [6.80, 7.78]	<1e-100	13022
5 years	0.01	12.13 [11.12, 13.24]	<1e-100	6248
1 year	0.01	28.16 [23.96, 33.11]	<1e-100	3068

Correlations

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Index endpoint: DM_COMORB – Diabetes-related co-morbidities/complications
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetes-related co-morbidities/complications
after Diabetes-related co-morbidities/complications

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Diabetes-related co-morbidities/complications

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