Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
SLE_COMORB
Extra metadata
First used in FinnGen datafreeze
DF2
SLE_COMORB
Similar endpoints
↥List of similar endpoints to
SLE-related co-morbidities
based on the number of shared cases.
Broader endpoints:
- Rheumatoid arthritis -related co-morbidities
- Psoriatic arthropathies related co-morbidities
- Diabetes-related co-morbidities/complications
- Rheumatological diseases related comorbidities
- Any ICDMAIN event in hilmo or causes of death
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52002 | 20636 | 31366 |
| Unadjusted prevalence (%) | 20.00 | 14.04 | 27.74 |
| Mean age at first event (years) | 62.45 | 63.28 | 61.91 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.07 | 5.22 [4.84, 5.63] | <1e-100 | 13692 |
| 15 years | 0.04 | 6.82 [6.36, 7.30] | <1e-100 | 11943 |
| 5 years | 0.01 | 12.91 [11.87, 14.04] | <1e-100 | 6241 |
| 1 year | 0.01 | 34.70 [29.74, 40.49] | <1e-100 | 3405 |
Correlations
↥
Index endpoint: SLE_COMORB – SLE-related co-morbidities
GWS hits:
Survival analyses between endpoints
↥Plot
before SLE-related co-morbidities
after SLE-related co-morbidities
Loading survival analyses plot
Table
Loading survival analyses table