Angina pectoris

Prinzmetal's angina: a syndrome typically consisting of angina (cardiac chest pain) at rest that occurs in cycles. It is caused by vasospasm, a narrowing of the coronary arteries caused by contraction of the smooth muscle tissue in the vessel walls rather than directly by atherosclerosis (buildup of fatty plaque and hardening of the arteries). For a portion of patients Prinzmetal's angina may be a manifestation of vasospastic disorder and is associated with migraine, Raynaud's phenomenon or aspirin-induced asthma.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I20
Hospital discharge: ICD-9 413|411[0-1]
Hospital discharge: ICD-8 413
Cause of death: ICD-10 I20
Cause of death: ICD-9 413|411[0-1]
Cause of death: ICD-8 413

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_ANGINA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I20-I25
Name in latin Angina pectoris

Summary Statistics

Key figures

All Female Male
Number of individuals 21934 7722 14212
Unadjusted prevalence (%) 8.44 5.25 12.57
Mean age at first event (years) 62.35 63.82 61.55


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.27 [2.05, 2.52] 1.7e-56 6042
15 years 0.02 2.64 [2.42, 2.88] <1e-100 5031
5 years 0.00 3.62 [3.31, 3.96] <1e-100 1884
1 year 0.00 5.50 [4.75, 6.36] <1e-100 561


Index endpoint: I9_ANGINA – Angina pectoris
GWS hits: 29

Survival analyses between endpoints


before Angina pectoris
after Angina pectoris

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