Ischaemic heart disease, wide definition

DOID EFO MESH SNOMED PheWeb

coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I20-I25

Hospital discharge: ICD-9 41[0-4]

Hospital discharge: ICD-8 41[0-4]

Cause of death: ICD-10 I21, I22, I23, I24, I25, I46, R96, R98

Cause of death: ICD-9 41[0-4]|798

Cause of death: ICD-8 41[0-4]|798

Cause of death: excluded ICD-9 7980A

KELA reimbursements: KELA codes 206

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

I9_IHD

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Ischaemic heart disease, wide definition based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	39313	14099	25214
Unadjusted prevalence (%)	15.12	9.59	22.30
Mean age at first event (years)	62.93	64.34	62.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.13 [3.79, 4.49]	<1e-100	11285
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: I9_IHD – Ischaemic heart disease, wide definition
GWS hits: 42

Survival analyses between endpoints

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Plot

before Ischaemic heart disease, wide definition
after Ischaemic heart disease, wide definition

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Table

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Drugs most likely to be purchased after Ischaemic heart disease, wide definition

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