Ischaemic heart disease, wide definition

coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I20-I25
Hospital discharge: ICD-9 41[0-4]
Hospital discharge: ICD-8 41[0-4]
Cause of death: ICD-10 I21, I22, I23, I24, I25, I46, R96, R98
Cause of death: ICD-9 41[0-4]|798
Cause of death: ICD-8 41[0-4]|798
Cause of death: excluded ICD-9 7980A
KELA reimbursements: KELA codes 206

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_IHD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 39313 14099 25214
Unadjusted prevalence (%) 15.12 9.59 22.30
Mean age at first event (years) 62.93 64.34 62.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.13 [3.79, 4.49] <1e-100 11285
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_IHD – Ischaemic heart disease, wide definition
GWS hits: 42

Survival analyses between endpoints

Plot

before Ischaemic heart disease, wide definition
after Ischaemic heart disease, wide definition

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Drugs most likely to be purchased after Ischaemic heart disease, wide definition