Myocardial infarction, strict

DOID EFO MESH SNOMED PheWeb

coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: only main entry used Yes

Hospital Discharge: ICD-10 I21, I22

Hospital discharge: ICD-9 410

Hospital discharge: ICD-8 410

Hospital discharge: excluded ICD-10 I21.90, I21.97, I22.90, I22.97

Cause of death: only main entry used Yes

Cause of death: ICD-10 I21, I22

Cause of death: ICD-9 410

Cause of death: ICD-8 410

Cause of death: excluded ICD-10 I21.90, I21.97, I22.90, I22.97

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

I9_MI_STRICT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Myocardial infarction, strict based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	14305	3958	10347
Unadjusted prevalence (%)	5.50	2.69	9.15
Mean age at first event (years)	64.92	68.88	63.40

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.21 [0.12, 0.36]	1.7e-8	5438
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: I9_MI_STRICT – Myocardial infarction, strict
GWS hits: 21

Survival analyses between endpoints

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Plot

before Myocardial infarction, strict
after Myocardial infarction, strict

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Table

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Drugs most likely to be purchased after Myocardial infarction, strict

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