Hard cardiovascular diseases

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

diagram bullet diagram downward connector

Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_CVD_HARD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 35849 12337 23512
Unadjusted prevalence (%) 13.79 8.40 20.79
Mean age at first event (years) 64.35 66.27 63.34

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.86 [5.35, 6.41] <1e-100 11457
15 years 0.05 7.25 [6.70, 7.83] <1e-100 10310
5 years 0.02 14.40 [13.25, 15.65] <1e-100 6038
1 year 0.01 44.69 [38.58, 51.78] <1e-100 3665

Correlations

Index endpoint: I9_CVD_HARD – Hard cardiovascular diseases
GWS hits: 21

Survival analyses between endpoints

Plot

before Hard cardiovascular diseases
after Hard cardiovascular diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hard cardiovascular diseases