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Diabetic neuropathy

DOIDEFOMESHSNOMED PheWeb

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E1[0-4]4
Hospital discharge: ICD-9 2505
Hospital discharge: ICD-8 25005
Cause of death: ICD-10 E1[0-4]4
Cause of death: ICD-9 2505
Cause of death: ICD-8 25005

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_NEUROPATHY

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diabetic neuropathy based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1769 669 1100
Unadjusted prevalence (%) 0.68 0.46 0.97
Mean age at first event (years) 54.76 52.26 56.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.63 [3.69, 8.61] 1.3e-15 498
15 years 0.04 5.99 [4.45, 8.07] 4.8e-32 432
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: DM_NEUROPATHY – Diabetic neuropathy
GWS hits: 1

Survival analyses between endpoints

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Plot

before Diabetic neuropathy
after Diabetic neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic neuropathy

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