Type 2 diabetes with neurological complications

DOID EFO MESH SNOMED PheWeb

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E11.4+, E11.4+G59.0, E11.4+G63.2, E11.4+G73.0, E11.4+G99.0

Hospital discharge: ICD-9 2505A

Cause of death: ICD-10 E11.4+, E11.4+G59.0, E11.4+G63.2, E11.4+G73.0, E11.4+G99.0

Cause of death: ICD-9 2505A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

E4_DM2NEU

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Type 2 diabetes with neurological complications based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1113	340	773
Unadjusted prevalence (%)	0.43	0.23	0.68
Mean age at first event (years)	62.35	62.90	62.10

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: E4_DM2NEU – Type 2 diabetes with neurological complications
GWS hits: 0

Survival analyses between endpoints

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Plot

before Type 2 diabetes with neurological complications
after Type 2 diabetes with neurological complications

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Table

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Drugs most likely to be purchased after Type 2 diabetes with neurological complications

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