Diabetes mellitus

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DIABETES

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Diabetes mellitus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 45235 20794 24441
Unadjusted prevalence (%) 17.40 14.15 21.61
Mean age at first event (years) 53.93 52.43 55.21


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.90 [2.63, 3.21] 2.8e-96 6751
15 years 0.02 3.25 [2.99, 3.54] <1e-100 5560
5 years 0.00 4.22 [3.87, 4.60] <1e-100 2092
1 year 0.00 5.57 [4.79, 6.48] <1e-100 527


Index endpoint: E4_DIABETES – Diabetes mellitus
GWS hits: 103

Survival analyses between endpoints


before Diabetes mellitus
after Diabetes mellitus

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Drugs most likely to be purchased after Diabetes mellitus