Diabetes mellitus

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

Filter registries None

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DIABETES

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Diabetes mellitus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

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Key figures

All Female Male
Number of individuals 45235 20794 24441
Unadjusted prevalence (%) 17.40 14.15 21.61
Mean age at first event (years) 53.93 52.43 55.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.90 [2.63, 3.21] 2.8e-96 6751
15 years 0.02 3.25 [2.99, 3.54] <1e-100 5560
5 years 0.00 4.22 [3.87, 4.60] <1e-100 2092
1 year 0.00 5.57 [4.79, 6.48] <1e-100 527

Correlations

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Index endpoint: E4_DIABETES – Diabetes mellitus
GWS hits: 103

Survival analyses between endpoints

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Plot

before Diabetes mellitus
after Diabetes mellitus

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Drugs most likely to be purchased after Diabetes mellitus

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