Type 2 diabetes

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 E11
Cause of death: ICD-10 E11
Medicine purchases: ATC A10B
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DM2

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) [obesus/non obesus] adultorum

Similar endpoints

List of similar endpoints to Type 2 diabetes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 41235 18715 22520
Unadjusted prevalence (%) 15.86 12.74 19.92
Mean age at first event (years) 58.43 57.57 59.14


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.81 [2.54, 3.10] 3.8e-91 6528
15 years 0.02 3.14 [2.89, 3.42] <1e-100 5469
5 years 0.00 4.19 [3.85, 4.56] <1e-100 2068
1 year 0.00 5.50 [4.74, 6.39] <1e-100 514


Index endpoint: E4_DM2 – Type 2 diabetes
GWS hits: 105

Survival analyses between endpoints


before Type 2 diabetes
after Type 2 diabetes

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