Type 2 diabetes without complications

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E11.9
Hospital discharge: ICD-9 2500A
Cause of death: ICD-10 E11.9
Cause of death: ICD-9 2500A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DM2NOCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E11

Summary Statistics

Key figures

All Female Male
Number of individuals 18832 7919 10913
Unadjusted prevalence (%) 7.24 5.39 9.65
Mean age at first event (years) 61.98 61.57 62.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.62 [4.02, 5.29] <1e-100 4820
15 years 0.04 5.30 [4.74, 5.92] <1e-100 4441
5 years 0.01 8.22 [7.47, 9.03] <1e-100 2442
1 year - - - -

Correlations

Index endpoint: E4_DM2NOCOMP – Type 2 diabetes without complications
GWS hits: 41

Survival analyses between endpoints

Plot

before Type 2 diabetes without complications
after Type 2 diabetes without complications

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Drugs most likely to be purchased after Type 2 diabetes without complications