Diabetes, varying definitions

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

diagram bullet diagram downward connector

Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 46087 21396 24691
Unadjusted prevalence (%) 17.72 14.56 21.83
Mean age at first event (years) 53.85 52.22 55.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.91 [2.64, 3.21] <1e-100 6838
15 years 0.02 3.25 [3.00, 3.53] <1e-100 5639
5 years 0.00 4.39 [4.04, 4.78] <1e-100 2154
1 year 0.00 6.05 [5.22, 7.02] <1e-100 570

Correlations

Index endpoint: DIABETES_FG – Diabetes, varying definitions
GWS hits: 106

Survival analyses between endpoints

Plot

before Diabetes, varying definitions
after Diabetes, varying definitions

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetes, varying definitions