Type1 diabetes, definitions combined

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

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Include endpoints

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Check conditions

not E4_DM2

Apply sex-specific rule None

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Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Type1 diabetes, definitions combined based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 3440 1703 1737
Unadjusted prevalence (%) 1.32 1.16 1.54
Mean age at first event (years) 18.38 17.49 19.25


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 9.13 [5.91, 14.12] 2.5e-23 141
15 years 0.08 11.79 [7.95, 17.49] 1.4e-34 109
5 years 0.02 18.93 [12.80, 28.00] 4.2e-49 44
1 year 0.01 27.23 [15.17, 48.87] 1.8e-28 13


Index endpoint: T1D – Type1 diabetes, definitions combined
GWS hits: 23

Survival analyses between endpoints


before Type1 diabetes, definitions combined
after Type1 diabetes, definitions combined

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Drugs most likely to be purchased after Type1 diabetes, definitions combined