Endpoint definition
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diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.
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List of similar endpoints to Type1 diabetes, definitions combined based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
All | Female | Male | |
---|---|---|---|
Number of individuals | 3440 | 1703 | 1737 |
Unadjusted prevalence (%) | 1.32 | 1.16 | 1.54 |
Mean age at first event (years) | 18.38 | 17.49 | 19.25 |
Follow-up | Absolute risk | HR [95% CI] | p | N |
---|---|---|---|---|
1998–2019 | 0.13 | 9.13 [5.91, 14.12] | 2.5e-23 | 141 |
15 years | 0.08 | 11.79 [7.95, 17.49] | 1.4e-34 | 109 |
5 years | 0.02 | 18.93 [12.80, 28.00] | 4.2e-49 | 44 |
1 year | 0.01 | 27.23 [15.17, 48.87] | 1.8e-28 | 13 |
Index endpoint: T1D – Type1 diabetes, definitions combined
GWS hits: 23
before Type1 diabetes, definitions combined
after Type1 diabetes, definitions combined
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