Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
T1D_WIDE
Extra metadata
First used in FinnGen datafreeze
DF2
Type 1 diabetes, wide definition
type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.
T1D_WIDE
Similar endpoints
↥List of similar endpoints to
Type 1 diabetes, wide definition
based on the number of shared cases.
Broader endpoints:
- Diabetes mellitus
- Diabetes, varying definitions
- Endocrine, nutritional and metabolic diseases
- Co-morbidites, CVD and metabolic diseases
- COPD Co-morbidites, CVD and metabolic diseases
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8611 | 3948 | 4663 |
| Unadjusted prevalence (%) | 3.31 | 2.69 | 4.12 |
| Mean age at first event (years) | 32.80 | 30.16 | 35.03 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.77 [2.86, 4.98] | 6.7e-21 | 1650 |
| 15 years | 0.03 | 4.00 [3.29, 4.86] | 5.0e-44 | 1272 |
| 5 years | 0.00 | 4.75 [4.07, 5.55] | 6.7e-86 | 466 |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: T1D_WIDE – Type 1 diabetes, wide definition
GWS hits: 33
Survival analyses between endpoints
↥Plot
before Type 1 diabetes, wide definition
after Type 1 diabetes, wide definition
Loading survival analyses plot
Table
Loading survival analyses table