Type 1 diabetes without complications

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E10.9
Hospital discharge: ICD-9 2500B
Cause of death: ICD-10 E10.9
Cause of death: ICD-9 2500B

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DM1NOCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 E10

Summary Statistics

Key figures

All Female Male
Number of individuals 6375 3098 3277
Unadjusted prevalence (%) 2.45 2.11 2.90
Mean age at first event (years) 27.71 26.21 29.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.69 [4.05, 7.99] 1.1e-23 636
15 years 0.04 6.21 [4.72, 8.17] 8.7e-39 486
5 years 0.01 8.45 [6.75, 10.59] 4.9e-77 183
1 year 0.00 11.66 [8.34, 16.30] 6.6e-47 51

Correlations

Index endpoint: E4_DM1NOCOMP – Type 1 diabetes without complications
GWS hits: 34

Survival analyses between endpoints

Plot

before Type 1 diabetes without complications
after Type 1 diabetes without complications

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Drugs most likely to be purchased after Type 1 diabetes without complications